SMAD4 ELISA Kit for Pig(Sus scrofa) | EIAab.comSMAD4 ELISA Kit for Pig(Sus scrofa)

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Index > Protein center > SMAD4(Gene name) > Pig

SMAD4 (Gene name),

Mothers against decapentaplegic homolog 4 (Protein name ), SMAD4_PIG from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SMAD4(MADH4);

Protein name:

Mothers against decapentaplegic homolog 4(MAD homolog 4;Mothers against DPP homolog 4);

Alternative:

SMAD family member 4(SMAD 4;Smad4);

Organism:

Pig (Sus scrofa).

General Annotation

Sub Unit:

Monomer (By similarity). Heterotrimer; with a C-terminally phosphorylated R-SMAD molecule and to form the transcriptionally active SMAD2/3-SMAD4 complex (By similarity). Found in a ternary complex composed of SMAD4, STK11/LKB1 and STK11IP. Interacts with ATF2, COPS5, DACH1, MSG1, SKI, STK11/LKB1, STK11IP and TRIM33. Associates with ZNF423 or ZNF521 in response to BMP2 leading to activate transcription of BMP target genes. Interacts with USP9X. Interacts with RBPMS. Interacts with WWTR1 (via coiled-coil domain). Interacts with CITED1 and CITED2.

Function:

Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor). Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. Component of the multimeric SMAD3/SMAD4/JUN/FOS complex which forms at the AP1 promoter site; required for syngernistic transcriptional activity in response to TGF-beta. May act as a tumor suppressor.

Subcellular Location:

Cytoplasm Nucleus In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with R-SMAD.

Protein Attributes:

Sequence length:

552

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

552:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Ssc.249

SMR:

Q9GKQ9

STRING:

9823.ENSSSCP00000004880

String:

Q9GKQ9

KEGG:

ssc:397142

Pfam:

PF03165

Uniprot:

Q9GKQ9

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ELISA Kit for Pig MAD homolog 4

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ELISA Kit for Pig MAD homolog 4

Cat.:

E1925r

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MSDS:

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Packing:

96T

ELISA Kit for Pig MAD homolog 4

Cat.:

E1925b

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MSDS:

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Packing:

96T

ELISA Kit for Pig MAD homolog 4

Cat.:

E1925m

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MSDS:

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Packing:

96T

ELISA Kit for Pig MAD homolog 4

Cat.:

E1925p

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MSDS:

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Packing:

96T

CLIA Kit for Pig MAD homolog 4

Cat.:

U1925m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Pig MAD homolog 4

Cat.:

U1925b

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Pig MAD homolog 4

Cat.:

U1925h

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MSDS:

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Packing:

96T

CLIA Kit for Pig MAD homolog 4

Cat.:

U1925p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Pig MAD homolog 4

Cat.:

U1925r

Price:

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MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Pig MAD homolog 4

Cat.:

P1925Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig MAD homolog 4

Cat.:

P1925Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig MAD homolog 4

Cat.:

P1925Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Pig MAD homolog 4

Protein for Pig MAD homolog 4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

Ito Y. , Awata T.
Submitted (2001-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Muscle.

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